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3SI7 Mouse NDB1 CFTR,delta F508 mutant

1)The alpha helices in pink and beta sheets shown in yellow make up the secondary structures. Regions that are without secondary structures are white. The CPK colored atoms are the structures of non proteins.
 2)ICL1 (residues 158-184) in cyan and ICL4 (residue 1050-1080) in green of CFTR.
 3)ATP of mouse NBD1 of CFTR


Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences
Mendoza, J.L., Schmidt, A., Li, Q., Nuvaga, E., Barrett, T., Bridges, R.J., Feranchak, A.P., Brautigam, C.A., Thomas, P.J.
Cell. 2012 Jan 20;148(1-2):164-74. doi: 10.1016/j.cell.2011.11.023.   

(PubMed)


3SI7 (PDB)

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